GHRHs are especially coupled with GHRPs to generate a synergy between the peptides that will unleash the body’s natural growth hormone reserves. Even though many peptides have some effect on their own, it is best to use GHRH in conjunction with a GHRP. This is why CJC 1295 is so popular in the bodybuilding world, and it’s one of the most commonly utilized. It’s now being discussed which CJC 1295 is the best to utilize. While MOD GRF (CJC 1295 no DAC) is routinely used with GHRPs to enhance pituitary GH pulse, it will require more frequent injections. A succession of smaller pulses will occur from the CJC 1295 with DAC.
Is it better to have a DAC or NO DAC?
When someone reads the word CJC 1295 without DAC, it truly implies they’re looking at MOD GRF 1-29. This tetrasubstituted peptide is a modified form of Sermorelin, the original GRF 1-29 peptide. Due to the original GRF 1-29’s extremely short half-life, scientists were able to alter the peptide to provide a prolonged biological activity while lowering metabolic clearance. Although the alteration of MOD GRF 1-29 resulted in a stronger peptide bond, the average user will still need to inject two to three times a day with a GHRP to get maximal endogenous growth hormone release. When the drug affinity complex (DAC) was introduced to CJC 1295, it opened up even more possibilities for using smaller GH pulses (what was formerly considered to be a bleed) that, when coupled with a GHRP, activate growth hormone reserves and release growth hormone throughout the day and night. When the DAC component was introduced, the peptide half-life was prolonged to nearly one week, and blood levels were more consistent following injection. Now that we know how essential the DAC component is, using CJC 1295 with DAC and a GHRP becomes a lot more realistic and cost-effective option. When the DAC is administered, it can connect to albumin that circulates throughout the body, allowing it to persist for days while it searches for receptors to bind to. In short, if you want shorter spikes of GH release, the MOD GRF 1-29 (CJC 1295 sans DAC) is the way to go. If you want fewer injections but still want to unlock the growth hormone reserves, injecting CJC 1295 with DAC 2-3 times per week combined with a daily injection of GHRP is the way to go.
Consequences
The usage of CJC 1295 has been linked to water retention, tingling, numbness, and low insulin levels. Tiredness, lethargy, exhilaration, and itching are other common symptoms. Improved lean body mass, enhanced protein synthesis, quicker recovery, reduced body fat, increased bone density, and cellular stimulation for internal organs and skin cells are all possible positive side effects.
Conclusion
Finally, CJC 1295 with DAC is a potent growth hormone-releasing hormone that may be used with a GHRP to get the maximum endogenous growth hormone release that subjects need. Despite the fact that CJC 1295 with DAC is more costly than MOD GRF 1-29 (CJC 1295 without DAC), it is the preferred and more potent GHRH component in the peptide protocol. Considering the difference between the two, in case you have a license, you can buy CJC-1295 NO DAC online and test it out for research purposes.
